Regulatory T Cells Orchestrate Similar Immune Evasion of Fetuses and Tumors in Mice
نویسندگان
چکیده
منابع مشابه
Regulatory T Cells Orchestrate Similar Immune Evasion of Fetuses and Tumors in Mice.
Embryos and tumors are both masses of dividing cells expressing foreign Ags, but they are not rejected by the immune system. We hypothesized that similar tolerogenic mechanisms prevent their rejection. Global comparison of fetal and tumor microenvironments through transcriptomics in mice revealed strikingly similar and dramatic decreases in expression of numerous immune-related pathways, includ...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2015
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.1501834